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Snail2 promotes osteosarcoma cell motility through remodelling of the actin cytoskeleton and regulates tumor development
The function of Snail2 in mesenchymal tumors is, to date unknown. Using knockdown and overexpression studies, we show that Snail2 regulates migration and invasion of osteosarcoma cells. Knockdown resulted in significantly decreased motility, remodelling of the actin cytoskeleton, and loss of cellula...
में बचाया:
| मुख्य लेखकों: | , , , , |
|---|---|
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
Elsevier Science Ireland
2013
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3644682/ https://ncbi.nlm.nih.gov/pubmed/23352643 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2013.01.027 |
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