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Mechanistic systems modeling to guide drug discovery and development

A crucial question that must be addressed in the drug development process is whether the proposed therapeutic target will yield the desired effect in the clinical population. Pharmaceutical and biotechnology companies place a large investment on research and development, long before confirmatory dat...

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Detalhes bibliográficos
Main Authors: Schmidt, Brian J., Papin, Jason A., Musante, Cynthia J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3644584/
https://ncbi.nlm.nih.gov/pubmed/22999913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drudis.2012.09.003
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