The 19-kilodalton adenovirus E1B transforming protein inhibits programmed cell death and prevents cytolysis by tumor necrosis factor alpha.

The adenovirus E1A and E1B proteins are required for transformation of primary rodent cells. When expressed in the absence of the 19,000-dalton (19K) E1B protein, however, the E1A proteins are acutely cytotoxic and induce host cell chromosomal DNA fragmentation and cytolysis, analogous to cells unde...

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Bibliografiske detaljer

Udgivet i:	Mol Cell Biol
Principais autores:	White, E, Sabbatini, P, Debbas, M, Wold, W S, Kusher, D I, Gooding, L R
Format:	Artigo
Sprog:	Inglês
Udgivet:	Taylor & Francis 1992
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC364450/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1317006/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.12.6.2570-2580.1992
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