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Deregulated c-myb disrupts interleukin-6- or leukemia inhibitory factor-induced myeloid differentiation prior to c-myc: role in leukemogenesis.

The c-myb proto-oncogene is abundantly expressed in tissues of hematopoietic origin, and changes in endogenous c-myb genes have been implicated in both human and murine hematopoietic tumors. c-myb encodes a DNA-binding protein capable of trans-activating the c-myc promoter. Suppression of both of th...

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Dettagli Bibliografici
Pubblicato in:Mol Cell Biol
Autori principali: Selvakumaran, M, Liebermann, D A, Hoffman-Liebermann, B
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 1992
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC364442/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1588953/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.12.6.2493-2500.1992
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