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Proteoglycans and their roles in brain cancer

Glioblastoma (GBM), a malignant brain cancer, is characterized by abnormal activation of receptor tyrosine kinase (RTK) signaling pathways and poor prognosis. Extracellular proteoglycans, including heparan sulfate and chondroitin sulfate, play critical roles in the regulation of cell signaling and m...

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Detalhes bibliográficos
Main Authors: Wade, Anna, Robinson, Aaron E., Engler, Jane R., Petritsch, Claudia, James, C. David, Phillips, Joanna J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3644380/
https://ncbi.nlm.nih.gov/pubmed/23281850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.12109
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