Proteoglycans and their roles in brain cancer

Glioblastoma (GBM), a malignant brain cancer, is characterized by abnormal activation of receptor tyrosine kinase (RTK) signaling pathways and poor prognosis. Extracellular proteoglycans, including heparan sulfate and chondroitin sulfate, play critical roles in the regulation of cell signaling and m...

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Bibliographic Details
Main Authors: Wade, Anna, Robinson, Aaron E., Engler, Jane R., Petritsch, Claudia, James, C. David, Phillips, Joanna J.
Format: Artigo
Language:Inglês
Published: 2013
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3644380/
https://ncbi.nlm.nih.gov/pubmed/23281850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.12109
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