Proteoglycans and their roles in brain cancer

Glioblastoma (GBM), a malignant brain cancer, is characterized by abnormal activation of receptor tyrosine kinase (RTK) signaling pathways and poor prognosis. Extracellular proteoglycans, including heparan sulfate and chondroitin sulfate, play critical roles in the regulation of cell signaling and m...

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Bibliografiske detaljer
Main Authors: Wade, Anna, Robinson, Aaron E., Engler, Jane R., Petritsch, Claudia, James, C. David, Phillips, Joanna J.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3644380/
https://ncbi.nlm.nih.gov/pubmed/23281850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.12109
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