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Does Pharmacogenomics Account for Variability in Control of Acute Chemotherapy-Induced Nausea and Vomiting with 5-Hydroxytryptamine Type 3 Receptor Antagonists?

Chemotherapy-induced nausea and vomiting is one of the most concerning adverse drug effects from cytotoxic chemotherapy. Despite appropriate use of antiemetic guidelines, 20–30% of patients experience breakthrough nausea and vomiting secondary to chemotherapy. To assess the variability of 5-hydroxyt...

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Autors principals: Trammel, Morgan, Roederer, Mary, Patel, Jai, McLeod, Howard
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3644374/
https://ncbi.nlm.nih.gov/pubmed/23512709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11912-013-0312-x
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