TRPV1-mediated UCP2 upregulation ameliorates hyperglycemia-induced endothelial dysfunction

BACKGROUND: Diabetic cardiovascular complications are characterised by oxidative stress-induced endothelial dysfunction. Uncoupling protein 2 (UCP2) is a regulator of mitochondrial reactive oxygen species (ROS) generation and can antagonise oxidative stress, but approaches that enhance the activity...

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Bibliografski detalji
Glavni autori: Sun, Jing, Pu, Yunfei, Wang, Peijian, Chen, Sijiao, Zhao, Yu, Liu, Chan, Shang, Qianhui, Zhu, Zhiming, Liu, Daoyan
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2013
Teme:
Original Investigation
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3644255/
https://ncbi.nlm.nih.gov/pubmed/23607427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2840-12-69
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