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Subversion of innate immune responses by Brucella through the targeted degradation of the TLR signaling adapter, MAL
Gram-negative bacteria belonging to the Brucella species cause chronic infections that can result in undulant fever, arthritis and osteomyelitis in humans. Remarkably, Brucella sp. genomes encode a protein, named TcpB, that bears significant homology with mammalian TIR (Toll/IL-1 receptor) domains a...
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| Auteurs principaux: | , , , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2009
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3644118/ https://ncbi.nlm.nih.gov/pubmed/20018612 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0902008 |
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