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Tension Sensing by Aurora B Kinase is Independent of Survivin-Based Centromere Localization

Accurate segregation of the replicated genome requires chromosome biorientation on the spindle. Biorientation is ensured by Aurora B kinase, a member of the 4-subunit chromosomal passenger complex (CPC)(1,2). Localization of the CPC to the inner centromere is central to the current model for how ten...

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Autors principals: Campbell, Christopher S., Desai, Arshad
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3644022/
https://ncbi.nlm.nih.gov/pubmed/23604256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature12057
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