Polygenic risk accelerates the developmental progression to heavy, persistent smoking and nicotine dependence: Evidence from a 4-Decade Longitudinal Study

OBJECTIVE: To test how genomic loci identified in genome-wide association studies (GWAS) influence the developmental progression of smoking behavior. DESIGN: A 38-year prospective longitudinal study of a representative birth-cohort. SETTING: The Dunedin Multidisciplinary Health and Development Study...

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Autores principales: Belsky, Daniel W, Moffitt, Terrie E, Baker, Timothy B, Biddle, Andrea K, Evans, James P, Harrington, HonaLee, Houts, Renate, Meier, Madeline, Sugden, Karen, Williams, Benjamin, Poulton, Richie, Caspi, Avshalom
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3644004/
https://ncbi.nlm.nih.gov/pubmed/23536134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamapsychiatry.2013.736
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