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MBNL1 and PTB cooperate to repress splicing of Tpm1 exon 3
Exon 3 of the rat α-tropomyosin (Tpm1) gene is repressed in smooth muscle cells, allowing inclusion of the mutually exclusive partner exon 2. Two key types of elements affect repression of exon 3 splicing: binding sites for polypyrimidine tract-binding protein (PTB) and additional negative regulator...
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Autors principals: | , , , , , , , , |
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Format: | Artigo |
Idioma: | Inglês |
Publicat: |
Oxford University Press
2013
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Matèries: | |
Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3643581/ https://ncbi.nlm.nih.gov/pubmed/23511971 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt168 |
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