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From single-SNP to wide-locus: genome-wide association studies identifying functionally related genes and intragenic regions in small sample studies
BACKGROUND: Genome-wide association studies (GWAS) have had limited success when applied to complex diseases. Analyzing SNPs individually requires several large studies to integrate the often divergent results. In the presence of epistasis, multivariate approaches based on the linear model (includin...
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| Main Authors: | , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2013
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3643309/ https://ncbi.nlm.nih.gov/pubmed/23438886 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/pgs.13.28 |
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