An alternatively processed mRNA from the avian c-erbB gene encodes a soluble, truncated form of the receptor that can block ligand-dependent transformation.

Ítems similars

• Native avian c-erbB gene expresses a secreted protein product corresponding to the ligand-binding domain of the receptor.
  per: Maihle, N J, et al.
  Publicat: (1991)
• Proviral insertional activation of c-erbB: differential processing of the protein products arising from two alternate transcripts.
  per: Maihle, N J, et al.
  Publicat: (1988)
• Mechanism of c-erbB transduction: newly released transducing viruses retain poly(A) tracts of erbB transcripts and encode C-terminally intact erbB proteins.
  per: Raines, M A, et al.
  Publicat: (1988)
• Molecular characterization of three erbB transducing viruses generated during avian leukosis virus-induced erythroleukemia: extensive internal deletion near the kinase domain activates the fibrosarcoma- and hemangioma-inducing potentials of erbB.
  per: Raines, M A, et al.
  Publicat: (1988)
• Ligand-independent dimerization of oncogenic v-erbB products involves covalent interactions.
  per: Adelsman, M A, et al.
  Publicat: (1996)