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Preclinical Alzheimer disease —the challenges ahead

There is growing recognition that the pathophysiological process of Alzheimer disease (AD) begins many years prior to clinically obvious symptoms, and the concept of a presymptomatic or preclinical stage of AD is becoming more widely accepted. Advances in biomarker studies have enabled detection of...

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Autors principals: Sperling, Reisa A., Karlawish, Jason, Johnson, Keith A.
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3643203/
https://ncbi.nlm.nih.gov/pubmed/23183885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrneurol.2012.241
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