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Frequency-Dependent Modes of Synaptic Vesicle Endocytosis and Exocytosis at Adult Mouse Neuromuscular Junctions

During locomotion, adult rodent lumbar motoneurons fire in high-frequency (80–100 Hz) 1–2 s bursts every several seconds, releasing between 10,000 and 20,000 vesicles per burst. The estimated total vesicle pool size indicates that all vesicles would be used within 30 s; thus, a mechanism for rapid e...

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Detalhes bibliográficos
Main Authors: Maeno-Hikichi, Yuka, Polo-Parada, Luis, Kastanenka, Ksenia V., Landmesser, Lynn T.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3642848/
https://ncbi.nlm.nih.gov/pubmed/21248134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2800-10.2011
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