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Histone methyl-transferases and demethylases; can they link metabolism and transcription ?
Epigenetics is defined as heritable changes to the transcriptome that are independent on changes in the genome. The biochemical principles that govern epigenetic modifications are DNA methylation and posttranslational modifications of histones, amongst which acetylation/deacetylation and methylation...
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| Main Authors: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2010
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3642811/ https://ncbi.nlm.nih.gov/pubmed/20889125 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2010.09.004 |
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