A dominant activating mutation in the effector region of RAS abolishes IRA2 sensitivity.

Previously described mutations in RAS genes that cause a dominant activated phenotype affect the intrinsic biochemical properties of RAS proteins, either decreasing the intrinsic GTPase or reducing the affinity for guanine nucleotides. In this report, we describe a novel activating mutation in the R...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Tanaka, K, Wood, D R, Lin, B K, Khalil, M, Tamanoi, F, Cannon, J F
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 1992
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC364252/
https://ncbi.nlm.nih.gov/pubmed/1732735
Tagiau: Ychwanegu Tag
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