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Methylene blue induces macroautophagy through 5′ adenosine monophosphate-activated protein kinase pathway to protect neurons from serum deprivation

Methylene blue has been shown to be neuroprotective in multiple experimental neurodegenerative disease models. However, the mechanisms underlying the neuroprotective effects have not been fully elucidated. Previous studies have shown that macroautophagy has multiple beneficial roles for maintaining...

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Hlavní autoři: Xie, Luokun, Li, Wenjun, Winters, Ali, Yuan, Fang, Jin, Kunlin, Yang, Shaohua
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3642497/
https://ncbi.nlm.nih.gov/pubmed/23653592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2013.00056
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