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Rab12 regulates mTORC1 activity and autophagy through controlling the degradation of amino-acid transporter PAT4

Autophagy is an evolutionarily conserved catabolic mechanism that targets intracellular molecules and damaged organelles to lysosomes. Autophagy is achieved by a series of membrane trafficking events, but their regulatory mechanisms are poorly understood. Here, we report small GTPase Rab12 as a new...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Matsui, Takahide, Fukuda, Mitsunori
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: European Molecular Biology Organization 2013
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3642374/
https://ncbi.nlm.nih.gov/pubmed/23478338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2013.32
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