Nuclear Factor κB Mediates Suppression of Canonical Transient Receptor Potential 6 Expression by Reactive Oxygen Species and Protein Kinase C in Kidney Cells

This study was carried out to explore the molecular mechanism for down-regulation of TRPC6 expression in the reactive oxygen species (ROS)/PKC signaling in kidney cells. In cultured human mesangial cells, H(2)O(2) and TNF-α inhibited TRPC6 mRNA expression in a time-dependent manner. Inhibition of NF...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Wang, Yanxia, Ding, Min, Chaudhari, Sarika, Ding, Yanfeng, Yuan, Joseph, Stankowska, Dorota, He, Shaoqing, Krishnamoorthy, Raghu, Cunningham, Joseph T., Ma, Rong
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2013
Gaiak:
Signal Transduction
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3642329/
https://ncbi.nlm.nih.gov/pubmed/23525112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.410357
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