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IMP3 Protein Promotes Chemoresistance in Breast Cancer Cells by Regulating Breast Cancer Resistance Protein (ABCG2) Expression

IMP3, a member of a family of insulin-like growth factor II (IGF-II) mRNA-binding proteins (IMPs), is expressed preferentially in triple-negative breast cancers, which are resistant to many chemotherapeutics. However, the mechanisms by which it impacts breast cancer have not been elucidated. We hypo...

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Bibliografiske detaljer
Main Authors: Samanta, Sanjoy, Pursell, Bryan, Mercurio, Arthur M.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3642304/
https://ncbi.nlm.nih.gov/pubmed/23539627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C112.442319
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