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Exploring potassium-dependent GTP hydrolysis in TEES family GTPases

GTPases are important regulatory proteins that hydrolyze GTP to GDP. A novel GTP-hydrolysis mechanism is employed by MnmE, YqeH and FeoB, where a potassium ion plays a role analogous to the Arginine finger of the Ras-RasGAP system, to accelerate otherwise slow GTP hydrolysis rates. In these proteins...

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Detalhes bibliográficos
Main Authors: Rafay, Abu, Majumdar, Soneya, Prakash, Balaji
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3642159/
https://ncbi.nlm.nih.gov/pubmed/23650596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.fob.2012.07.008
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