Group B Streptococcus Hijacks the Host Plasminogen System to Promote Brain Endothelial Cell Invasion

Group B Streptococcus (GBS) is the leading cause of meningitis in neonates. We have previously shown that plasminogen, once recruited to the GBS cell surface and converted into plasmin by host-derived activators, leads to an enhancement of bacterial virulence. Here, we investigated whether plasmin(o...

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Main Authors: Magalhães, Vanessa, Andrade, Elva Bonifácio, Alves, Joana, Ribeiro, Adilia, Kim, Kwang Sik, Lima, Margarida, Trieu-Cuot, Patrick, Ferreira, Paula
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3642152/
https://ncbi.nlm.nih.gov/pubmed/23658816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0063244
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