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Modification of Histone Acetylation Facilitates Hepatic Differentiation of Human Bone Marrow Mesenchymal Stem Cells

The multi-potentiality of mesenchymal stem cells makes them excellent options for future tissue engineering and clinical therapy, including liver injury. In this study, we investigated the effects of valproic acid (VPA), a direct inhibitor of histone deacetylase (HDAC), on the hepatic differentiatio...

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Detalhes bibliográficos
Main Authors: Dong, Xuejun, Pan, Ruolang, Zhang, Hui, Yang, Chao, Shao, Jianzhong, Xiang, Lixin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3642107/
https://ncbi.nlm.nih.gov/pubmed/23658825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0063405
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