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Modeling and Measuring Signal Relay in Noisy Directed Migration of Cell Groups

We develop a coarse-grained stochastic model for the influence of signal relay on the collective behavior of migrating Dictyostelium discoideum cells. In the experiment, cells display a range of collective migration patterns, including uncorrelated motion, formation of partially localized streams, a...

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Autori principali: Guven, Can, Rericha, Erin, Ott, Edward, Losert, Wolfgang
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3642071/
https://ncbi.nlm.nih.gov/pubmed/23658506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003041
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