A Novel Hyaluronidase from Brown Spider (Loxosceles intermedia) Venom (Dietrich's Hyaluronidase): From Cloning to Functional Characterization

Loxoscelism is the designation given to clinical symptoms evoked by Loxosceles spider's bites. Clinical manifestations include skin necrosis with gravitational spreading and systemic disturbs. The venom contains several enzymatic toxins. Herein, we describe the cloning, expression, refolding an...

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Autori principali: Ferrer, Valéria Pereira, de Mari, Thiago Lopes, Gremski, Luiza Helena, Trevisan Silva, Dilza, da Silveira, Rafael Bertoni, Gremski, Waldemiro, Chaim, Olga Meiri, Senff-Ribeiro, Andrea, Nader, Helena Bonciani, Veiga, Silvio Sanches
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2013
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3642055/
https://ncbi.nlm.nih.gov/pubmed/23658852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0002206
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