A Novel Hyaluronidase from Brown Spider (Loxosceles intermedia) Venom (Dietrich's Hyaluronidase): From Cloning to Functional Characterization

Loxoscelism is the designation given to clinical symptoms evoked by Loxosceles spider's bites. Clinical manifestations include skin necrosis with gravitational spreading and systemic disturbs. The venom contains several enzymatic toxins. Herein, we describe the cloning, expression, refolding an...

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Autors principals: Ferrer, Valéria Pereira, de Mari, Thiago Lopes, Gremski, Luiza Helena, Trevisan Silva, Dilza, da Silveira, Rafael Bertoni, Gremski, Waldemiro, Chaim, Olga Meiri, Senff-Ribeiro, Andrea, Nader, Helena Bonciani, Veiga, Silvio Sanches
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3642055/
https://ncbi.nlm.nih.gov/pubmed/23658852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0002206
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