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ApoE Isoform-Dependent Deficits in Extinction of Contextual Fear Conditioning
The three major human apoE isoforms (apoE2, apoE3, and apoE4) are encoded by distinct alleles (ε2, ε3, and ε4). Compared to ε3, ε4 is associated with increased risk to develop Alzheimer’s disease (AD), cognitive impairments in Parkinson’s disease (PD), and other conditions. In contrast, a recent stu...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3642038/ https://ncbi.nlm.nih.gov/pubmed/22883220 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1601-183X.2012.00833.x |
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