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Pilot trial of bone-targeted therapy combining zoledronate with fluvastatin or atorvastatin for patients with metastatic renal-cell carcinoma

OBJECTIVE: The biologic rationale for this study came from the observation that bisphosphonates and statins affect bone metastasis in different ways; thus, combination therapy may provide synergistic benefit. This pilot trial evaluated the efficacy and safety of combining a bisphosphonate and statin...

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Detalhes bibliográficos
Main Authors: Manoukian, George E., Tannir, Nizar M., Jonasch, Eric, Qiao, Wei, Haygood, Tamara M., Tu, Shi-Ming
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3641665/
https://ncbi.nlm.nih.gov/pubmed/21958521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clgc.2011.07.001
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