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Deferoxamine restores callus size, mineralization and mechanical strength in fracture healing after radiotherapy

BACKGROUND: Therapeutic augmentation of fracture site angiogenesis with Deferoxamine (DFO) has proven to increase vascularity, callus size and mineralization in long-bone fracture models. We posit that the addition of DFO would enhance pathological fracture healing in the setting of radiotherapy in...

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Detalhes bibliográficos
Main Authors: Donneys, Alexis, Ahsan, Salman, Perosky, Joseph E., Deshpande, Sagar S., Tchanque-Fossuo, Catherine N., Levi, Benjamin, Kozloff, Ken M., Buchman, Steven R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3641519/
https://ncbi.nlm.nih.gov/pubmed/23629110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/PRS.0b013e3182865c57
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