A genetic effect of IL-5 receptor α polymorphism in patients with aspirin-exacerbated respiratory disease

Persistent eosinophil activation in both the upper and lower airway mucosa is a central feature of aspirin-exacerbated respiratory disease (AERD). Eosinophil activation and survival are profoundly influenced by interleukin 5 (IL-5) and its receptor, IL-5R. In patients susceptible to allergic disorde...

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Hlavní autoři: Losol, Purevsuren, Kim, Seung-Hyun, Seob Shin, Yoo, Min Ye, Young, Park, Hae-Sim
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2013
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3641394/
https://ncbi.nlm.nih.gov/pubmed/23470716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emm.2013.24
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