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Sirt1 improves healthy ageing and protects from metabolic syndrome-associated cancer syndrome
Genetic overexpression of the protein deacetylase Sir2 increases longevity in a variety of lower organisms, and this has prompted a great interest on the effects of its closest mammalian homologue, Sirt1, on aging and cancer. We have generated transgenic mice moderately overexpressing Sirt1 under it...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3641391/ https://ncbi.nlm.nih.gov/pubmed/20975665 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms1001 |
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