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Genetic variant in the telomerase gene modifies cancer risk in Lynch syndrome
Lynch syndrome (LS) is an inherited cancer-predisposing disorder caused by germline mutations in the mismatch repair (MMR) genes. The high variability in individual cancer risk observed among LS patients suggests the existence of modifying factors. Identifying genetic modifiers of risk could help im...
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| 主要な著者: | , , , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3641380/ https://ncbi.nlm.nih.gov/pubmed/22948024 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2012.204 |
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