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Retinoic acid represses invasion and stem cell phenotype by induction of the metastasis suppressors RARRES1 and LXN

The mouse haematopoietic stem cell (SC) regulator Latexin (LXN) is the only known homologue of the retinoic acid receptor responder 1 (RARRES1) gene. Both genes lie adjacent on chromosome 3 and differ mostly by the presence of a transmembrane domain in RARRES1. Despite their homology, it is not know...

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Detalhes bibliográficos
Main Authors: Oldridge, E E, Walker, H F, Stower, M J, Simms, M S, Mann, V M, Collins, A T, Pellacani, D, Maitland, N J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3641360/
https://ncbi.nlm.nih.gov/pubmed/23588494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/oncsis.2013.6
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