PGE(2) suppresses NK activity in vivo directly and through adrenal hormones: Effects that cannot be reflected by ex-vivo assessment of NK cytotoxicity

Surgery can suppress in vivo levels of NK cell cytotoxicity (NKCC) through various mechanisms, including catecholamine-, glucocorticoid (CORT)-, and prostaglandin (PG)-mediated responses. However, PGs are synthesized locally following tissue damage, driving proinflammatory and CORT responses, while...

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Bibliografiske detaljer
Main Authors: Meron, G., Tishler, Y., Shaashua, L., Rosenne, E., Levi, B., Melamed, R., Gotlieb, N., Matzner, P., Sorski, L., Ben-Eliyahu, S.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3641317/
https://ncbi.nlm.nih.gov/pubmed/23153554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbi.2012.11.003
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