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A New Rapid Methodological Strategy to Assess BRCA Mutational Status
Hereditary cancers account for approximately 10 % of breast and ovarian cancers. Mutations of the BRCA1 and BRCA2 genes, encoding two proteins involved in DNA repair, underlie most cases of such hereditary cancers. Women with BRCA mutations develop breast cancer in 50–80 % of cases and ovarian cance...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Humana Press Inc
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3641296/ https://ncbi.nlm.nih.gov/pubmed/23354980 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12033-012-9646-0 |
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