The mouse Wnt-1 gene can act via a paracrine mechanism in transformation of mammary epithelial cells.

The mouse Wnt-1 gene plays an essential role in fetal brain development and can contribute to tumorigenesis when activated aberrantly in the mammary gland. The gene encodes secretory glycoproteins associated with the extracellular or pericellular matrix, and it has been proposed that Wnt-1, as well...

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Bibliographic Details
Main Authors: Jue, S F, Bradley, R S, Rudnicki, J A, Varmus, H E, Brown, A M
Format: Artigo
Language:Inglês
Published: 1992
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC364112/
https://ncbi.nlm.nih.gov/pubmed/1530877
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