ARID1A Alterations Are Associated with FGFR3-Wild Type, Poor-Prognosis, Urothelial Bladder Tumors

Urothelial bladder cancer (UBC) is heterogeneous at the clinical, pathological, genetic, and epigenetic levels. Exome sequencing has identified ARID1A as a novel tumor suppressor gene coding for a chromatin remodeling protein that is mutated in UBC. Here, we assess ARID1A alterations in two series o...

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Detalhes bibliográficos
Main Authors: Balbás-Martínez, Cristina, Rodríguez-Pinilla, María, Casanova, Ariel, Domínguez, Orlando, Pisano, David G., Gómez, Gonzalo, Lloreta, Josep, Lorente, José A., Malats, Núria, Real, Francisco X.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3641081/
https://ncbi.nlm.nih.gov/pubmed/23650517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0062483
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