Enhanced IL-6/IL-6R Signaling Promotes Growth and Malignant Properties in EBV-Infected Premalignant and Cancerous Nasopharyngeal Epithelial Cells

Nasopharyngeal carcinoma (NPC) is etiologically associated with Epstein-Barr virus (EBV) infection. However, the exact role of EBV in NPC pathogenesis remains elusive. Activation of signal transducer and activator of transcription 3 (STAT3) is common in human cancers including NPC and plays an impor...

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Detalhes bibliográficos
Main Authors: Zhang, Guitao, Tsang, Chi Man, Deng, Wen, Yip, Yim Ling, Lui, Vivian Wai-Yan, Wong, Sze Chuen Cesar, Cheung, Annie Lai-Man, Hau, Pok Man, Zeng, Musheng, Lung, Maria Li, Chen, Honglin, Lo, Kwok Wai, Takada, Kenzo, Tsao, Sai Wah
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3641047/
https://ncbi.nlm.nih.gov/pubmed/23658720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0062284
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