Decreased reticuloendothelial system clearance and increased blood half-life and immune cell labeling for nano- and micron-sized superparamagnetic iron-oxide particles upon pre-treatment with Intralipid

BACKGROUND: Superparamagnetic iron-oxide nanoparticles are useful as contrast agents for anatomical, functional and cellular MRI, drug delivery agents, and diagnositic biosensors. Nanoparticles are generally cleared by the reticuloendothelial system (RES), in particular taken up by Kupffer cells in...

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Detalhes bibliográficos
Main Authors: Liu, Li, Hitchens, T. Kevin, Ye, Qing, Wu, Yijen, Barbe, Brent, Prior, Devin E., Li, Wendy F., Yeh, Fang-Cheng, Foley, Lesley M., Bain, Daniel J., Ho, Chien
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3640706/
https://ncbi.nlm.nih.gov/pubmed/23396002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagen.2013.01.021
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