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Inhibition of Pref-1 (Preadipocyte Factor 1) by Estradiol in Adolescent Girls with Anorexia Nervosa is Associated with Improvement in Lumbar Bone Mineral Density

OBJECTIVE: Adolescents with anorexia nervosa (AN) are amenorrheic and have decreased bone mass accrual and low bone mineral density (BMD). The regulation of mesenchymal stem cell differentiation is an important factor governing bone formation. Preadipocyte factor 1 (Pref-1), an inhibitor of adipocyt...

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Detalhes bibliográficos
Main Authors: Faje, Alexander T., Fazeli, Pouneh K., Katzman, Debra, Miller, Karen K, Breggia, Anne, Rosen, Clifford J., Mendes, Nara, Misra, Madhusmita, Klibanski, Anne
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3640659/
https://ncbi.nlm.nih.gov/pubmed/23331192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cen.12144
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