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TREX1 acts in degrading damaged DNA from drug-treated tumor cells
The major mammalian exonuclease TREX1 has been proposed to play a role in DNA repair and drug resistance. However, no cellular evidence substantiates this claim. Recent reports indicate TREX1’s involvement in autoimmunity. To further understand its role, we studied TREX1 expression and functionality...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3640554/ https://ncbi.nlm.nih.gov/pubmed/19617005 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2009.06.006 |
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