Cytogenetic Abnormalities in Multiple Myeloma: Poor Prognosis Linked to Concomitant Detection in Random and Focal Lesion Bone Marrow Samples and Associated with High-Risk Gene Expression Profile

The clinical significance of cytogenetic abnormalities (CA) present in randomly sampled (RS) or focal lesion (FL) bone marrow sites was examined in 419 untreated myeloma patients. Among 290 patients with gene expression profiling (GEP) data generated from RS sites, GEP-defined high-risk was present...

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Main Authors: Zhou, Yiming, Nair, Bijay, Shaughnessy, John D, Cartron, Marie-Astrid, Haessler, Jeff, Anaissie, Elias, van Rhee, Frits, Crowley, John, Barlogie, Bart
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3640347/
https://ncbi.nlm.nih.gov/pubmed/19344415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2141.2009.07670.x
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