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Diminished mitochondrial DNA integrity and repair capacity in OA chondrocytes
OBJECTIVES: Osteoarthritis (OA) is characterized by the failure of chondrocytes to respond to injury and perform the cartilage remodeling process. Human articular chondrocytes actively produce reactive oxygen and nitrogen species (ROS and RNS) capable of causing cellular dysfunction and death. A gro...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3640312/ https://ncbi.nlm.nih.gov/pubmed/18562218 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.joca.2008.05.009 |
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