The Regulation of Apoptosis by the Downstream Regulatory Element Antagonistic Modulator/Potassium Channel Interacting Protein 3 (DREAM/KChIP3) Through Interactions with Hexokinase I

The EF-hand protein, DREAM/KChIP3 (henceforth referred to as DREAM), regulates apoptosis by incompletely understood mechanisms. We demonstrate that in the presence of Ca(2+), DREAM interacts with hexokinase I, a protein known to bind mitochondria and regulate apoptosis. A mutant DREAM protein constr...

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Hauptverfasser: Craig, Theodore A., Ramachandran, Pradeep L., Bergen, H. Robert, Podratz, Jewel L, Windebank, Anthony J., Kumar, Rajiv
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3640266/
https://ncbi.nlm.nih.gov/pubmed/23524266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2013.03.016
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