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Structural Insights into a Wildtype Domain of the Oncoprotein E6 and Its Interaction with a PDZ Domain
The high-risk human papilloma virus (HPV) oncoproteins E6 and E7 interact with key cellular regulators and are etiological agents for tumorigenesis and tumor maintenance in cervical cancer and other malignant conditions. E6 induces degradation of the tumor suppressor p53, activates telomerase and de...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3640046/ https://ncbi.nlm.nih.gov/pubmed/23638119 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0062584 |
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