Exploratory Bioinformatics Study of lncRNAs in Alzheimer's Disease mRNA Sequences with Application to Drug Development

Long noncoding RNA (lncRNA) within mRNA sequences of Alzheimer's disease genes, namely, APP, APOE, PSEN1, and PSEN2, has been analyzed using fractal dimension (FD) computation and correlation analysis. We examined lncRNA by comparing mRNA FD to corresponding coding DNA sequences (CDSs) FD. APP,...

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Detalles Bibliográficos
Main Authors: Holden, T., Nguyen, A., Lin, E., Cheung, E., Dehipawala, S., Ye, J., Tremberger, G., Lieberman, D., Cheung, T.
Formato: Artigo
Idioma:Inglês
Publicado: Hindawi Publishing Corporation 2013
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3639631/
https://ncbi.nlm.nih.gov/pubmed/23662159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/579136
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