5-Lipoxygenase Activity Increases Susceptibility to Experimental Paracoccidioides brasiliensis Infection

Paracoccidioidomycosis (PCM) is a systemic mycosis caused by the thermodimorphic fungus Paracoccidioides brasiliensis. Leukotrienes and lipoxins are lipid mediators produced after 5-lipoxygenase (5-LO) activation that exhibit pro- and anti-inflammatory roles, respectively. Here, we have investigated...

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Autors principals: Tristão, Fabrine Sales Massafera, Rocha, Fernanda Agostini, Moreira, Ana Paula, Cunha, Fernando Queiroz, Rossi, Marcos Antonio, Silva, João Santana
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2013
Matèries:
Fungal and Parasitic Infections
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3639621/
https://ncbi.nlm.nih.gov/pubmed/23381993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01209-12
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