RfaL Is Required for Yersinia pestis Type III Secretion and Virulence

Yersinia pestis, the causative agent of plague, uses a type III secretion system (T3SS) to inject cytotoxic Yop proteins directly into the cytosol of mammalian host cells. The T3SS can also be activated in vitro at 37°C in the absence of calcium. The chromosomal gene rfaL (waaL) was recently identif...

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Autors principals: Houppert, Andrew S., Bohman, Lesley, Merritt, Peter M., Cole, Christopher B., Caulfield, Adam J., Lathem, Wyndham W., Marketon, Melanie M.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2013
Matèries:
Molecular Pathogenesis
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3639585/
https://ncbi.nlm.nih.gov/pubmed/23357388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01417-12
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