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Major contribution of sarcoplasmic reticulum Ca(2+) depletion during long-lasting activation of skeletal muscle

Depolarization of skeletal muscle fibers induces sarcoplasmic reticulum (SR) Ca(2+) release and contraction that progressively decline while depolarization is maintained. Voltage-dependent inactivation of SR Ca(2+) release channels and SR Ca(2+) depletion are the two processes proposed to explain th...

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Detalhes bibliográficos
Main Authors: Robin, Gaëlle, Allard, Bruno
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3639577/
https://ncbi.nlm.nih.gov/pubmed/23630339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201310957
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