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The food dye FD&C Blue No. 1 is a selective inhibitor of the ATP release channel Panx1

The food dye FD&C Blue No. 1 (Brilliant Blue FCF [BB FCF]) is structurally similar to the purinergic receptor antagonist Brilliant Blue G (BBG), which is a well-known inhibitor of the ionotropic P2X7 receptor (P2X7R). The P2X7R functionally interacts with the membrane channel protein pannexin 1...

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Detalhes bibliográficos
Main Authors: Wang, Junjie, Jackson, David George, Dahl, Gerhard
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3639576/
https://ncbi.nlm.nih.gov/pubmed/23589583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201310966
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